It is known to stimulate detoxifying enzymes in the gut and liver. Because diets high in these vegetables slow cancer growth in animals, I3C is thought to be a good candidate for cancer prevention. Lab studies suggest that I3C may have activity across various tumor types. What does indole-3-carbinol do for estrogen?
Studies increasingly indicate that dietary indole-3-carbinol (I3C) prevents the development of estrogen-enhanced cancers including breast, endometrial and cervical cancers. Epidemiological, laboratory, animal and translational studies support the efficacy of I3C.
These findings suggest that I3C has a potential benefit in preventing obesity and metabolic disorders, and the action for I3C in vivo may involve multiple mechanisms including decreased adipogenesis and inflammation, along with activated thermogenesis.
Hence, I3C appears to reduce estrogen activity by multiple mechanisms. Our present findings highlight the potential of this phytochemical for both the prevention and treatment of estrogen-enhanced cancers.
Does indole-3-carbinol balance hormones?
Indole-3-Carbinol balances hormone levels, improves breast health, detoxifies the intestines and liver, and supports the immune system.
I3C is taken preferably with meals since this nutrient's effects are activated by stomach acid and the acidity is a usual response from food.
Cruciferous vegetables contain sulforaphane. Sulforaphane is a chemical that is made when chewing cruciferous vegetables such as broccoli, cauliflower, and broccoli sprouts. A chemical in these vegetables called glucoraphanin mixes with an enzyme in humans called myrosinase, which produces sulforaphane.
What does sulforaphane do for the body?
Sulforaphane has been shown to reduce the ability of cancerous cells to multiply. That means it may slow tumor growth or reduce its ability to spread to other parts of your body. It is readily available. You don't have to do anything complicated to access the sulforaphane in cruciferous vegetables.
Sulforaphane increases the expression of the dihydrotestosterone (DHT)-degrading enzyme, 3±-hydroxysteroid dehydrogenase (3±-HSD) in the liver, which accelerates DHT degradation, thereby inhibiting hair loss in the animal model.
Sulforaphane targets Nrf2 pathway to prevent kidney disease progression.
What does sulforaphane do to the brain? Multiple in vitro and in vivo studies have demonstrated the ability of SFN to prevent various brain diseases, including stroke, TBI, AD, PD, and ASD. SFN exerts neuroprotective effects, at least in a part, through activating Nrf2 signaling pathway and its downstream antioxidative as well as antitoxic enzymes.
Most of those who responded to sulforaphane showed significant improvements by the first measurement at four weeks and continued to improve during the rest of the treatment.
The precursor and sulforaphane are resistant to heat and therefore cooking, but the enzyme is destroyed. No enzyme = no sulforaphane.
Does sulforaphane reverse aging?
Sulforaphane is a very potent and bioavailable Nrf2 pathway activator, via KEAP1 protein. Sulforaphane lowers DNA damage by reducing oxidative stress and inflammation, processes that are central to cancer, aging, brain diseases and other diseases of aging.
Does sulforaphane affect sleep?
Sulforaphane increases melatonin production, which may enhance quality of sleep. Sulforaphane decreases prostaglandin D2 levels, which causes inflammation. Sulforaphane may improve sleep by increasing melatonin and anti-inflammation.
Does sulforaphane detox the liver?
Additionally, sulforaphane enhances detoxification activity in the body by inducing enzymes involved in metabolism of harmful toxins by the liver, promoting their elimination.
Does sulforaphane detox the body?
Compounds in foods, such as sulforaphane, induce the enzymes involved in phase I and phase II detoxification, playing an important role in reducing the impact of environmental toxins.
What food is sulforaphane highest in?
Best Source of Sulforaphane: Broccoli
Sulforaphane can be obtained from all cruciferous vegetables like kale, cauliflower or kohlrabi, with broccoli being the best source by far. Broccoli sprouts may be up to 25 times more potent than regular raw broccoli.
Does indole-3-carbinol lower cholesterol?
These results demonstrate that (a) I3C lowers serum cholesterol levels at concentrations that have no discernible effect on hepatic cholesterol homoeostasis, and (b) at higher doses of I3C, hepatic microsomal cholesterol levels are significantly lowered and ACAT activity is significantly elevated.
What is the number one supplement to lower cholesterol? Niacin
12 Foods that Shrink Benign Tumors [Anti-Cancer Diet Guide]
1. Turmeric (With a dash of black pepper.)
2 Green Tea Catechins are antioxidants found in the leaves of the tea plant, Camellia sinensis. They are great for cancer prevention as they protect cells from being damaged by free radicals.
3 Cruciferous vegetables
4. Walnuts Walnuts are rich in polyphenols which are metabolized by the body into urolithins. Urolithins are compounds that have shown the ability to help in preventing prostate cancer development and proliferation.
Additionally, recent research suggests that adding walnuts to your healthy diet may be beneficial in preventing breast cancer. Marshall University’s study found that eating two ounces of nuts per day for two weeks reduced breast cancer risk and lowered the chance of developing it.
5 Berries Berries are high in vitamins and minerals. The antioxidants found in berries are particularly strong. They can stop free radicals from damaging your cells, and can also prevent cancer from spreading or growing.
A study posted in the US National Library of Medicine has shown that anthocyanin (a blackberry compound) lowers biomarkers of colon cancer cells. Another study shows that blueberries have anti-inflammatory properties that inhibit the metastasis of triple-negative breast cancer cells.
6. Tomatoes .Tomatoes have high levels of lycopene, an effective antioxidant. This compound is responsible for the vibrant red color and its anti-cancer properties.
Numerous studies have shown that a higher intake of tomatoes and lycopene could reduce the risk of developing prostate and lung cancer. The body may absorb lycopene more easily from tomato sauces than processed tomatoes.
7. Fatty fish
Regular fish consumption promises various health benefits, including a reduced risk of developing cancer.
Fatty fish such as salmon, mackerel, and anchovies are rich in vitamin B, vitamin D, potassium, and Omega-3 essential nutrients that can help your body to fight cancer.
One study showed that people who eat a lot of freshwater fish have a 53 percent lower chance of developing colorectal cancer (also known as colon cancer).
Another study showed that the consumption of fish oil of elderly men is linked to significantly lower risks for prostate cancer. 8. Folate-rich food
Normal cells can become malignant tumors if there are abnormalities in their DNA.
Eating foods rich in folate, a vitamin B-complex, helps with DNA formation and repair.
Research has shown that folate deficiencies can damage the DNA which increases the risk of certain types of cancer. On the contrary, sufficient folate levels can be effective protection against the risk of cancer cell growth.
These are some sources of folate to help you fight the risk of cancer:
Broccoli
Brussels sprouts
Leafy green vegetables
Peas
Chickpeas, kidney beans
Grain products with folic acids
9. Legumes The fiber in legumes like beans, peas, and lentils may lower the risk of getting cancer. Beans contain anti-inflammatory, antioxidant, and cancer-fighting substances that may protect cells against damage and slow down the growth of benign tumor cells.
Research shows that people who consume high amounts of bean fiber were 20% less likely to develop breast carcinoma than those with lesser intake.
10: Whole wheat. would avoid it as it is sprayed with Glyphosate to kill it. Also wheat and potatoes convert to sugar in the body and can make you fat.
11. Garlic and olive oil
Both garlic and olive oil have so many potential health benefits that they became staples in the kitchen of people who are following a diet rich in cancer-fighting substances.
Numerous studies have shown that an increase in olive oil and garlic intake may be potent against cancer.
A massive review of 19 studies found that those who ate the most olive oil had a lower chance of developing breast cancer or cancer of the digestive tract.
It is easy to swap out other oils for olive oil and reap the health benefits. It can be drizzled over salads, cooked vegetables, and marinades for meat, poultry, and fish.
Although it is difficult to prove a direct connection between garlic consumption and cancer prevention, the National Cancer Institute suggests that increased intake of garlic can be associated with lower risks of breast, stomach, esophagus, pancreas, and colorectal cancer.
12. Water
Generally, all of us should drink an adequate amount of water daily to avoid dehydration. Your body can’t function properly if there’s not enough fluid.
Fluid consumption has many benefits, including:
controlling your heart rate and blood pressure
maintaining your body’s temperature
eliminating toxins and waste
protecting the organs, tissues, and joints transporting nutrients and oxygen around the body
Poster Comment:
Organic vegetables have salvesterols that kill fungi that attack plants. In humans they prevent cancer.